Thursday, May 28, 2009
Glowing Monkeys Make More Glowing Monkeys
The first genetically modified primates that can pass their modifications to their offpsring have been created by Japanese scientists.
The marmosets, pictured above, express a green fluorescent protein in their skin. The gene for producing the glow was delivered to the first marmoset embryos via a modified virus. But now that modification method could become unnecessary. One male marmoset fathered a child (pictured at right) that also contained the transgenes.
Transgenic animals are a key tool in the biomedical researchers’ toolbox. They allow scientists to model the function of genes and the efficacy of treatments. Many transgenic mice lines exist, but often the small rodents are too different from humans to effectively extrapolate their responses to human beings. Primates, on the other hand, are far closer biologically to humans, but before the new technique, creating primate models had proven difficult and expensive.
Now, biologists may be able to produce whole groups of marmosets that mimic humans with genetic diseases like cystic fibrosis.
Original article here.
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